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Donika Ivanova Selected Research

2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate

1/2022Effect of Alpha-tocopheryl Succinate on the Cytotoxicity of Anticancer Drugs Towards Leukemia Lymphocytes.
1/2018Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib.
1/2017Synergistic Cytotoxicity of Melatonin and New-generation Anticancer Drugs Against Leukemia Lymphocytes But Not Normal Lymphocytes.
11/2016Inhibition of the Pentose-phosphate Pathway Selectively Sensitizes Leukemia Lymphocytes to Chemotherapeutics by ROS-independent Mechanism.
4/2016Docosahexaenoic Acid Sensitizes Leukemia Lymphocytes to Barasertib and Everolimus by ROS-dependent Mechanism Without Affecting the Level of ROS and Viability of Normal Lymphocytes.
12/20152-Deoxy-D-glucose Sensitizes Cancer Cells to Barasertib and Everolimus by ROS-independent Mechanism(s).

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Donika Ivanova Research Topics

Disease

7Neoplasms (Cancer)
01/2020 - 11/2013
6Leukemia
01/2022 - 12/2015
3Mitochondrial Diseases (Mitochondrial Disease)
01/2018 - 12/2015
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 04/2016
1Body Weight (Weight, Body)
02/2022
1Melanoma (Melanoma, Malignant)
01/2020
1Atherosclerosis
10/2017
1Inflammation (Inflammations)
10/2017
1Carcinogenesis
11/2013

Drug/Important Bio-Agent (IBA)

7Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018 - 12/2015
62- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphateIBA
01/2022 - 12/2015
5Pharmaceutical PreparationsIBA
01/2022 - 01/2017
5EverolimusFDA Link
01/2018 - 12/2015
3Proteins (Proteins, Gene)FDA Link
01/2018 - 12/2015
2lonafarnib (SCH 66336)IBA
01/2022 - 04/2016
2Succinic Acid (Succinate)IBA
01/2022 - 01/2020
2Vitamin K 3 (Menadione)FDA Link
01/2020 - 01/2018
2Superoxides (Superoxide)IBA
01/2020 - 12/2015
2Ascorbic Acid (Vitamin C)FDA LinkGeneric
01/2018 - 01/2018
2Free RadicalsIBA
10/2017 - 11/2013
1Benzoic Acid (Potassium Benzoate)FDA Link
02/2022
1SilymarinIBA
02/2022
1Bortezomib (Velcade)FDA Link
01/2022
1Drug CombinationsIBA
01/2020
1LigandsIBA
01/2020
1NAD (NADH)IBA
01/2020
1Dicumarol (Dicoumarol)FDA Link
01/2020
1Adenosine Triphosphate (ATP)IBA
01/2020
1quinone (benzoquinone)IBA
01/2020
1Cytostatic AgentsIBA
01/2020
1CalciumIBA
01/2018
1Vitamin KFDA Link
01/2018
1VitaminsIBA
01/2018
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
10/2017
1MelatoninIBA
01/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2017
16-Aminonicotinamide (6 Aminonicotinamide)IBA
11/2016
1palbociclibIBA
04/2016
1Docosahexaenoic AcidsIBA
04/2016
1nitroxylIBA
12/2015
1RotenoneIBA
12/2015
12-MethoxyestradiolIBA
12/2015
1TEMPOIBA
12/2015
1Deoxyglucose (2 Deoxy D glucose)IBA
12/2015

Therapy/Procedure

3Therapeutics
01/2022 - 11/2013
2Drug Therapy (Chemotherapy)
01/2018 - 01/2018
1Oral Administration
01/2020
1Aftercare (After-Treatment)
04/2016